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TO THE PROBLEM OF FORMATION OF OCCUPATIONAL BRONCHI AND LUNGS CANCER DIAGNOSIS IN CLINIC FOR OCCUPATIONAL DISEASES

TO THE PROBLEM OF FORMATION OF OCCUPATIONAL BRONCHI AND LUNGS CANCER DIAGNOSIS IN CLINIC FOR OCCUPATIONAL DISEASES

3(27) 2011

https://doi.org/10.33573/ujoh2011.03.003

Varyvonchyk D. V.

TO THE PROBLEM OF FORMATION OF OCCUPATIONAL BRONCHI AND LUNGS CANCER DIAGNOSIS IN CLINIC FOR OCCUPATIONAL DISEASES

SI «Institute for Occupational Health of NAMS of Ukraine», Kiev

Full article (PDF), UKR

The studies showed that bronchi and lungs cancer (BLC), pneumoconiosis (PC), chronic bronchitis of dust etiology (CB), chronic obstructive lungs diseases (COLD) in clinical diagnosis of patients with occupational pathology should be referred to main concurrent diseases. Bronchi and lungs cancer is not a complication of chronic non-specific pathology of respiration organs of dust genesis as a result of different pathogenesis of these nosological units. In its turn, chronic non-specific pathology of respiration organs of the dust genesis is referred to cancer diseases (faculty pre-cancer diseases) because of common etiology with BLC and formation of favorable pathogenetic background in realization of mechanisms of epigenetic carcinogenesis as a result of cumulation and long-term preservation of mediators of chronic inflammation in bronchi and lungs tissues (IL-1, TNF-a, IFN-g).

Keywords: formation of the clinical diagnosis, bronchi and lungs cancer, pneumoconiosis, chronic bronchitis, chronic obstructive lungs disease, etiology, pathogenesis

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