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COMPARATIVE STUDY OF THE CONTENT AND SIZE OF CIRCULATING IMMUNE COMPLEXES IN BLOOD SERUM IN EXPERIMENTAL TOXIC, DUST AND TOXICO-DUST BRONCHITIS IN RATS

COMPARATIVE STUDY OF THE CONTENT AND SIZE OF CIRCULATING IMMUNE COMPLEXES IN BLOOD SERUM IN EXPERIMENTAL TOXIC, DUST AND TOXICO-DUST BRONCHITIS IN RATS

1(17) '2009

https://doi.org/10.33573/ujoh2009.01.065

Krushevsky V.D.1, Stezhka V.A.2

COMPARATIVE STUDY OF THE CONTENT AND SIZE OF CIRCULATING IMMUNE COMPLEXES IN BLOOD SERUM IN EXPERIMENTAL TOXIC, DUST AND TOXICO-DUST BRONCHITIS IN RATS

1Ukrainian Scientific-Research Institute of Industrial Medicine, Kryvoi Rog

2State Institution «Institute for Occupational Health of AMS of Ukraine», Kyiv

Full article (PDF), UKR

In the dynamics of experimental toxic (NOx; S02), dust (large-dispersive Si02; amorphous hydrofobic Si02) and toxico-dust (amorphous hydrofobic Si02+NOx; amorphous hydrofobic Si02+S02) chronic bronchitis in 350 rats a comparative research of peculiarities of cumulation in blood serum and sizes of circulating immune complexes (CIC) was conducted. It was estab­lished that for pathogenesis of such experimentally reproduced pathological states at the stage of chronisation,e production and cumulation in blood serum of most pathogenic average-molecular CIC is specific.

Key words: toxic, dust, toxico-dust chronic bronchitis, circulating immune complexes, rats

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